OFC Ancestry-specific Meta-analysis GWAS Summary Statistics (GWAS-SSF TSV)

OVERVIEW
This folder contains :
1) ancestry-specific meta-analysis results, and
2) ancestry-specific, dataset-specific GWAS results from three datasets (OFC1, OFC2, and Beaty TDT)


PHENOTYPES (5 SUBTYPES)
Results are provided for the following OFC subtypes : any, cl, clp, cp, clclcp


ANCESTRY GROUPS
Ancestry is indicated in filenames:
- AFRICAN
- ASIAN
- CAUCASIAN
- LATINSOUTHAMERICAN

FILES

1) Ancestry-specific meta-analysis results
- meta_ancestry_<SUBTYPE>_<ANCESTRY>_GWAS-SSF.tsv
  Description: Ancestry-specific meta-analysis summary statistics for subtype <SUBTYPE> within ancestry group <ANCESTRY>.

  Columns:
  - chromosome: Chromosome number
  - base_pair_location: Genomic position (bp)
  - effect_allele: Effect allele
  - other_allele: Other allele
  - beta: Estimated effect size 
  - standard_error: Standard error of beta
  - effect_allele_frequency: Frequency of effect_allele
  - p_value: Association p-value


2) Dataset-specific GWAS results 

- ofc1_gwas_ancestry_<SUBTYPE>.<ANCESTRY>_GWAS-SSF.tsv
  Description: OFC1 ancestry-specific GWAS summary statistics for subtype <SUBTYPE> within ancestry group <ANCESTRY>.

- ofc2_gwas_ancestry_<SUBTYPE>.<ANCESTRY>_GWAS-SSF.tsv
  Description: OFC2 ancestry-specific GWAS summary statistics for subtype <SUBTYPE> within ancestry group <ANCESTRY>.

- beaty_tdt_ancestry_<SUBTYPE>.<ANCESTRY>_GWAS-SSF.tsv
  Description: Beaty TDT (family-based) ancestry-specific GWAS summary statistics for subtype <SUBTYPE> within ancestry group <ANCESTRY>.

  Columns:
  - chromosome: Chromosome number
  - base_pair_location: Genomic position (bp)
  - effect_allele: Effect allele
  - other_allele: Other allele
  - Est: Effect estimate 
  - n.obs: Number of observations
  - effect_allele_frequency: Frequency of effect_allele
  - p_value: Association p-value



CONTACT
Xinyi Zhang
